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Glycosmedia Weekly Diabetes News - 08/27/2021

HDL and type 2 diabetes: the chicken or the egg?

HDL, the sleeping beauty of lipoproteins, is waiting for its prince to awake her therapeutic potential (Diabetologia)


Major adverse cardiovascular and limb events in patients with diabetes treated with GLP-1 receptor agonists vs DPP-4 inhibitors

In individuals with diabetes, the use of GLP1RAs was associated with significantly lower risks of major adverse limb events when compared with the use of DPP4is … Moreover, treatment with GLP1RAs was also associated with lower risks of cardiovascular death, non-fatal stroke, non-fatal myocardial infarction and death from any cause (Diabetologia)


Effects of canagliflozin on serum potassium in people with diabetes and chronic kidney disease: the CREDENCE trial

Among patients treated with renin–angiotensin–aldosterone system inhibitors, SGLT2 inhibition with canagliflozin may reduce the risk of hyperkalaemia in people with T2DM and CKD without increasing the risk of hypokalaemia (European Heart Journal)


Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials

GLP-1 receptor agonists, regardless of structural homology, reduced the risk of individual MACE components, all-cause mortality, hospital admission for heart failure, and worsening kidney function in patients with type 2 diabetes (The Lancet Diabetes & Endocrinology)


Relationship between Hyponatremia and Peripheral Neuropathy in Patients with Diabetes

Low serum sodium levels were independently associated with DPN, even within the normal range of the serum sodium. We should pay more attention to avoid the low serum sodium level in patients with type 2 diabetes mellitus (Journal of Diabetes Research)


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Comment on recently published papers written by the medical editors of Glycosmedia.

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