We provide clear evidence of the modifying effect of diabetes on cardiometabolic risk factor associations with retinal microvascular architecture. These observations suggest the occurrence of preclinical disease processes, and may be a sign of impaired autoregulation due to hyperglycaemia, which has been suggested to play a pivotal role in the development of diabetes-related microvascular complications (Diabetologia) The study documented benefits of semaglutide on metabolic control and multiple CV risk factors, simplification of therapeutic schemes and high satisfaction with diabetes treatment, and eating behaviors indicative of healthy diet and reduced food intake (Acta Diabetologica) Collectively, the numerous glycemic and nonglycemic characteristics of the GLP-1 receptor agonist class of medications provide a strong rationale for their use in the treatment of many people with type 2 diabetes, as recommended by the ADA (Clinical Diabetes) Our results show that initial screening for islet autoantibodies at two ages (2 years and 6 years) is sensitive and efficient for public health translation but might require adjustment by country on the basis of population-specific disease characteristics (The Lancet Diabetes & Endocrinology)
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