| October 28, 2021 Wendy J.Weber,N.D., Ph.D., M.P.H. Robin ElizabethBoineau,M.D., M.A. The National Institutes of Health (NIH) Health Care Systems Research Collaboratory (HCS Collaboratory) just published a new funding opportunity announcement (FOA) to solicit phased cooperative research applications to conduct efficient large-scale pragmatic or implementation trials embedded within health care systems: RFA-AT-22-001:NIH Health Care Systems Research Collaboratory Pragmatic and Implementation Trials of Embedded Interventions (UG3/UH3, Clinical Trials Optional). As mentioned in two previous blog posts (The NIH Health Care Systems Research CollaboratoryNew Funding Opportunities for Health Systems ResearchersandNIH Collaboratory Expands Its Portfolio of Pragmatic Clinical Trials), the National Center for Complementary and Integrative Health (NCCIH) and the National Institute on Aging (NIA) have been leading theHCS Collaboratory(initiated as an NIH Common Fund program). The HCS Collaboratory has pioneered approaches for conducting large-scale, cost-effective randomized pragmatic trials in the health care settings where patients normally receive their care. | 