No football last night, but the NFL couldn't even let us enjoy the night off. Le'Veon Bell grabbed the headlines Thursday evening by signing with the Chiefs after narrowing his list of teams down throughout the day. And Fantasy players … probably wish he had made a different choice. 

I'm more pessimistic about what this signing means for Clyde Edwards-Helaire's Fantasy value than I expected to be, and you can read about why below. Plus, I've got my game previews for Week 6 ready to rock, with updates on the latest injuries, advice on the toughest lineup decisions and what I'll be watching for in each game. 

And, as always, if you want to send in a question — about your lineup, about trade offers, about life — hit me up at Chris.Towers@CBSInteractive.com with the subject line "#AskFFT" and you may find an answer in Sunday morning's newsletter.

Here's everything else you need to get ready for Week 6: Start 'Em & Sit 'Em | QB | RB  |  WR | Starts and sits, sleepers and busts | PPR Cheat Sheet |  Non-PPR Cheat Sheet | QB Preview | RB Preview |  WR Preview |  TE Preview | Biggest Questions | Waivers |  Cut List |  Trade Values | Winners and Losers | Believe It or Not

Le'Veon Bell opted to sign with the Chiefs on a one-year deal over reported multi-year offers from the Dolphins. Bell joins a Chiefs backfield where more than three-quarters of the touches have gone to Clyde Edwards-Helaire so far. Here's what you need to know:

• What it means for Bell: He gets maybe the biggest head coaching upgrade imaginable going from Adam Gase to Andy Reid, who is sure to figure out how to use the multi-talented veteran. And, with the Chiefs not playing until Monday in Week 6, it's possible Bell can get in the facility quickly enough to be available to debut this week. He'll be a PPR flex when he's active. 
• What it means for Edwards-Helaire: The floor and ceiling are both lower. Edwards-Helaire was dominating work for the Chiefs, earning 77% of their running back touches, which makes it even more disappointing that he was only 20th in PPR scoring per game at running back. It's entirely possible he remains in that range with Bell taking touches, because he's bound to play better moving forward, but the dreams of a top-five finish seem just about dead with this one. Edwards-Helaire is more in that low-end No. 2 RB discussion now. 
• What it means for the Chiefs: They get an upgrade at least for the backup running back spot, and Bell's three-down skill set especially figures to help since they don't trust Edwards-Helaire as a blocker yet. This just makes the most dangerous offense in the NFL that much more dangerous, though it will be interesting to see if they respond to this move by funneling more touches toward their backs and away from their wide receivers and tight ends. 
• What it means for Fantasy: There is probably some value in trying to acquire both Bell and CEH right now, because whoever has them right now might be worried this is going to be a quagmire that dooms them both to irrelevance. Maybe that's so, but as friend of FFT Ben Gretch said Thursday, "Both are worth kicking the tires on in any active trading league. Perception varies wildly on this one." I agree.

All lines from William Hill Sportsbook. For more game-by-game Fantasy advice, check out Dave Richard's Week 6 preview. "The line wants us to believe" from Dave Richard. 

On bye: Saints, Raiders, Seahawks, Chargers

• Line: MIN -4; o/u 54.5
• Implied totals: ATL 25.25 MIN 29.25
• The line wants us to believe: The Vikings aren't as good as their near-win at Seattle suggests. Sure, the Vkings work as a home favorite despite its one-win record, but couldn't the oddsmakers give them a few more points? They want you to bet on the Vikings, so they must figure Todd Gurley and the Falcons will keep it close. If Julio Jones plays, they might be right.
• Toughest lineup decision: Justin Jefferson — Start. Dave has him as a sit for this week, and I can understand the logic, but … it's the Falcons! How can you not start someone with Jefferson's upside against a matchup like this? 
• What we're watching for: Assuming Julio Jones isn't able to come back, can someone besides Calvin Ridley step up? Russell Gage looked like that guy early on, but he's dealt with injuries of his own and hasn't made an impact since Week 3. 
• Injuries: Dalvin Cook (groin) —Did not practice Wednesday or Thursday. Cook is expected to sit out, with the bye week allowing two weeks to recover. Alexander Mattison is Jamey Eisenberg's Start of the Week in his absence … Julio Jones (hamstring) — Did not practice Wednesday or Thursday, seems like a long shot to play this week … Hayden Hurst (back) — Would have been a limited participant if the Falcons had practiced Thursday. He should be good to go, but you can't really trust him as anything more than a low-end play at this point.  

• Line: PHI +7.5; o/u 47.5
• Implied totals: PHI 20, BAL 27.5
• The line wants us to believe: Philadelphia just isn't very good. They had to give the Eagles a bunch of points just to get some action on them. But it's interesting -- the Ravens' wins have all been by at least two scores and the Eagles' losses have been by at least nine points. Carson Wentz is supposed to keep this game close? Playing behind THAT offensive line?! The Ravens seem like a safe pick, but they will have a tough time running the ball in the early going.
• Toughest lineup decision: Travis Fulgham — Sit. I think there's a good chance Fulgham is a starter for the Eagles moving forward — ESPN's Adam Caplan said he expects as much Thursday — and there's a non-zero chance he's a Fantasy starter, too. But one good week isn't enough to gain your trust against this kind of matchup. 
• What we're watching for: How Fulgham gets used seems like the key thing to watch, especially if Alshon Jeffery and DeSean Jackson return. He stepped up in a big way when the Eagles needed him most, something not many other receivers can say. Do they reward him by sticking by him even as they get healthy? 
• Injuries: Alshon Jeffery (foot)/DeSean Jackson (hamstring) — Both remain limited in practice, as has been the case since last week. You're probably going to need to see a full practice before you can consider either as likely to return, but you won't want to rely on either until they prove they are healthy and productive either way. 

• Line: Panthers -1.5; o/u 45.
• Implied totals: CHI 21.75, CAR 23.25
• The line wants us to believe: The Panthers' turn-around is more impressive than the Bears 4-1 record. I think the oddsmakers know that the public knows the Bears aren't as good as their record says. And yet, they enter this matchup with a healthier roster, especially on defense. So if no one's buying the Bears, then why are they just 1.5 point underdogs? The Bears DST is a sneaky good option this week.
• Toughest lineup decision: D.J. Moore — Start. We actually got some questions about Moore and whether you should start him on our Thursday afternoon Start/Sit stream on Twitch, and I'm sticking with him. The Bears haven't allowed many points to wide receivers so far, but they also haven't played many good ones. Moore's role has been frustrating, but he's still getting downfield targets, and I'll still trust him as a WR3. 
• What we're watching for: There aren't really many questions about these two teams right now, but I want to see the Bears continue to use David Montgomery like they have the last few weeks. His role makes him a must-start Fantasy option, but any loss of passing game work could spell trouble.  
• Injuries: Curtis Samuel (knee) — Has been a limited participant in practice but should be able to play through it. 

Note: The Colts have been sent home this week due to positive COVID tests in their facility, so keep in mind that game may be moved, though nothing has come up yet.  

• Line: IND -8; o/u 46.5
• Implied totals: CIN 19.25, IND 27.25
• The line wants us to believe: The Colts are the far better team, even with Philip Rivers quarterbacking. Honestly, it's a testament to the rest of their squad, because this line feels fair (the public is leaning toward the Bengals). The Bengals lost defensive tackle D.J. Reader, making their already vulnerable run defense even weaker. Jonathan Taylor is a DFS cheat code.
• Toughest lineup decision: Joe Mixon — Start. I'm stubborn, and I can't justify sitting someone who is getting 30 touches per game like Mixon has the last two. His lowest total of the season? 19. There just aren't enough running backs getting consistent work to sit Mixon, matchups be damned. 
• What we're watching for: A.J. Green seems like he'll be healthy enough to play in Week 6, but at what point do the Bengals start to phase him out? He's been one of the least productive receivers in the NFL on a per-target basis, and admitted his frustration with his play and the team's record get to him when he made a lackluster effort to tackle Marcus Peters when his lone target was picked off in Week 5. Tee Higgins has already overtaken Green for the No. 2 job, but if Green starts to get phased out, that could mean even better days are ahead. 
• Injuries: A.J. Green (hamstring) — Has been limited at practice so far this week, but told reporters he expects to play … Mo Alie-Cox (knee) — Alie-Cox was already losing snaps before this injury, and no matter what his status is, he probably doesn't need to be rostered for Fantasy right now. 

• Line: PIT -3; o/u 51.0
• Implied totals: CLE 24, PIT 27
• The line wants us to believe: The Browns are for real, but Pittsburgh has found ways to win each week, and it's been by more than a field goal. So why only three points? They could have gotten away with at least minus-4.5. As tempted as I am to say the Steelers are a sucker bet, I just believe they're a better put-together team. Baker Mayfield's been a little too inaccurate to give the Browns a real shot. I'm also not sure the Browns can hit their implied team total of 24 points.
• Toughest lineup decision: Chase Claypool — Start. It's fair to wonder just how much work Claypool is going to get moving forward after his big Week 5. After all, Diontae Johnson and JuJu Smith-Schuster aren't exactly bums, here. Claypool may return to being more of a role player if Johnson is healthy, but I'll take the chance starting him in the hopes that he's established himself as a consistent part of this offense. 
• What we're watching for: It's that wide receiver hierarchy in Pittsburgh. Johnson looked like the No. 1 guy early on, but has had trouble staying healthy over the past three weeks. Smith-Schuster has had a secondary role all season, despite playing pretty well. Is Claypool the new No. 1? Does Johnson get back to dominating targets? Or can Smith-Schuster earn a bigger role? All three look like WR3 options to me this week. 
• Injuries: Odell Beckham (illness) — Beckham was sent home from practice Thursday with an illness. He took a COVID test before leaving the facility, but we won't know the results until Friday. Obviously, this is something to keep an eye on moving into Week 6, and not just for Beckham's sake … Jarvis Landry (hip/ribs) — Did not practice Wednesday or Thursday, so there's a real chance he may not play this week. Rashard Higgins was third on the team among WR in snaps in Week 5, but wouldn't be much more than a desperation play if either Beckham or Landry (or both!) sits out …Diontae Johnson (back) — Johnson was back at practice Thursday on a limited basis after sitting out Wednesday. We'll see if he gets a full practice in Friday, but this is the direction you want to see him moving … Eric Ebron (hand) — Upgraded to a full participant in practice, so this seems like a non-issue … Baker Mayfield (chest) — Limited again Thursday, but there's no sign this injury is expected to keep Mayfield out. 

• Line: NE -10; o/u 45.0
• Implied totals: DEN 17.5, NE 27.5
• The line wants us to believe: The Patriots will mop the floor with the Broncos, and they might -- getting Cam Newton back upped the line from minus-9 to minus-10. The Broncos won't be able to run as much as they want to against this good front seven, and Drew Lock should be good for a couple of turnovers.
• Toughest lineup decision: Patriots backfield — Sit. Maybe you start Damien Harris or James White in a deep league if you're desperate, but right now, this looks like a three-way backfield split next to a quarterback who dominates red zone looks, which makes it awfully tough for anyone to stand out. 
• What we're watching for: How will the Broncos handle Melvin Gordon, who was cited for a DUI earlier this week? He practiced Thursday and seems likely to play, but coach Vic Fangio told reporters "there will be some consequences" for Gordon. He likely won't face any discipline from the league until his legal proceedings are finished, but will the Broncos opt to bench him for a quarter as punishment? With Phillip Lindsay set to return from his foot injury this week, it's hard to know what the workload split will look like in Denver. 
• Injuries: Cam Newton (COVID/Reserve list) — Newton was cleared to return earlier this week and will step back into the starting lineup for the Patriots … Drew Lock (shoulder) — Full participant in practice Wednesday and Thursday, and is on track to return assuming he can avoid any kind of setback. That's great news for the rest of the offense … Noah Fant (ankle) — Limited both Wednesday and Thursday. You'd like to see him get a full practice in Friday to feel good about his chances of playing, but right now I would lean toward Fant not playing. … KJ Hamler (hamstring) — Did not practice either day. His absence could be a few weeks. 

• Line: JAC +3; o/u 54.5
• Implied totals: JAC 25.75, DET 28.75
• The line wants us to believe: The Jaguars are toast. Meanwhile, does anyone remember how the Lions fell apart in their last game? They got pummeled! Now you're supposed to lay points with them on the road?! Yep ... that's EXACTLY what they want you to think. Detroit's rested and the Jaguars are beat up on both sides of the ball. I also think both implied team totals (Jaguars 25.75, Lions 28.75) are too high
• Toughest lineup decision: Lions backfield — Sit. That could change if Adrian Peterson's illness (non-COVID related) lingers, but the most likely outcome is we continue to deal with a frustrating three-way split like we have when everyone here has been healthy. In Week 4, that meant 44% snaps and 9.6 Fantasy points for Peterson, 38% snaps and 15.2 points for D'Andre Swift, and 18% and 2.2 points for Kerryon Johnson. Peterson and Swift at both flex options in Non-PPR and PPR, but neither is a must-start by any definition. 
• What we're watching for: I want to see Matthew Stafford be more aggressive. We saw a little bit of that in Week 4 when his average intended air yards jumped to 10.5 per attempt, compared to below 9.0 in each of the first three games. He was above 9.0 yards (averaged 10.6) in all but one game last season, and it helped fuel his impressive performance before the injury. Maybe a fully healthy Kenny Golladay is the key to unlocking things. I like Stafford for this week and as a buy-low candidate long term. 
• Injuries: D.J. Chark (ankle) — Did not practice Wednesday or Thursday, seems likely to miss Week 6 … Laviska Shenault (hamstring) —  Upgraded to limited Thursday, which is a good sign, though not a guarantee. A full practice Friday would be a welcome sign. 

• Line: TEN -3; o/u 52.5 
• Implied totals: HOU 24.75, TEN 27.75
• The line wants us to believe: The Texans will stay close with their division rival. At this point I completely believe in the Titans. Practice? Who needs it?! Lean on Derrick Henry? Nah, not a requirement. They're an incredibly good team offensively and they were ballhawks on defense. The Texans offense should keep rolling, but it's the Texans defense that figures to fall back to earth.
• Toughest lineup decision: David Johnson — Start. But I would be apprehensive about it. The best case for Johnson so far has been his workload, but Romeo Crennel did talk about possibly getting Duke Johnson more involved. Still, coming off a 96-yard game, you probably have to trust David Johnson here. 
• What we're watching for: That Texans backfield, for sure, but also Brandin Cooks' role after his huge breakout in Week 5. Do they continue to use him like a go-to player, or was that more of a function of the matchup? Both Cooks and Will Fuller can be viewed as viable starters this week. 
• Injuries: A.J. Brown (knee) — All of a sudden, this looks like a legitimate concern as Brown hasn't practiced yet this week. With a short week, it could be an issue to watch for Friday. Darrynton Evans (hamstring) — Placed on injured reserve Thursday, meaning he'll be out at least three weeks. Jeremy McNichols (ribs) was limited Thursday but should be Henry's primary backup … Jordan Akins (ankle/concussion) — Limited practice Thursday but not yet cleared to play.

• Line: NYG -2.5; o/u 43.0
• Implied totals: WAS 20.25, NYG 22.75
• The line wants us to believe: The Giants' close games against the Cowboys and Rams make them the better team. Part of me thinks the oddsmakers could have gotten away with more points for the Giants. Enough to make me think this is a sucker line? Maybe a little, but Washington just keeps getting blown out. They shouldn't get close to their 20.25 implied points, making it easier for the G-Men to pull away for their first win.
• Toughest lineup decision: Antonio Gibson — Start. This is another one I wish I could be more confident in, but J.D. McKissic out snapped him in the second half last week. Perhaps that was just to give Alex Smith a more reliable veteran presence, but it sure was frustrating to see. Still, Gibson has five targets in each of his past two games, and if Washington can keep this one close, he should continue to see the bulk of the work on the ground, so this could be a good spot for him to bounce back. 
• What we're watching for: That Washington backfield might be the only thing worth watching here, honestly. We'd like to see Kyle Allen stay healthy and actually look like an improvement over Dwayne Haskins, or else this is going to be a pretty ugly scenario for Gibson and Terry McLaurin. 
• Injuries: Darius Slayton (foot) — Limited at practice both Wednesday and Thursday, so we'll want to keep an eye out for Friday to see if he makes any progress. Slayton is a viable starting option if healthy … Kyle Allen (shoulder) — Looks like he's going to be back in the starting role, which is good news, because Smith looked understandably overmatched in his first game in nearly two years … Antonio Gibson (toe) — Upgraded to a full participant Thursday, so no worries here. 

• Line: MIA -9.5; o/u 47.0
• Implied totals: NYJ 18.75, MIA 28.25
• The line wants us to believe: The Jets can keep it close ... well, close for them. I honestly think they could have gone with minus-13.5 and had about even action. That suggests it's a sucker line to take the Dolphins, but I'm walking right toward it. The Jets will show signs of life once they send Adam Gase packing. Too bad the team opted to send Le'Veon Bell packing first.
• Toughest lineup decision: Myles Gaskin — Start. Gaskin looked like he might lose his job with the Dolphins if Bell had come aboard, but he looks safe. Or at least, as safe as a player who nobody had pegged as the starter and whose team just tried to replace him can be. 
• What we're watching for: The Jets receiving corps may finally be close to getting healthy, so we'll want to watch how Jamison Crowder gets used once they have other options. My guess is, he's still the No. 1 guy, because that's how Adam Gase has always used his slot receivers. We'll also want to watch the Jets backfield with Bell out of the picture. It was mostly Frank Gore in the games Bell missed, but maybe they'll start to give rookie La'Mical Perine more of a look now. Perine is worth an add as a "get-ahead-of-the-waiver-wire" guy. 
• Injuries: Sam Darnold (shoulder) — Did not practice again Thursday. This will almost certainly be another Joe Flacco start … Breshad Perriman (ankle) — Limited at practice yet again Friday. He'll probably need a full practice to get cleared, so maybe it won't happen this week after all. Friday will be key … Denzel Mims (hamstring) — Mims is increasing his work after being designated to return from injured reserve, but he's also no guarantee to play in Week 6. In fact, it's probably more likely than not that he does not. 

• Line: Pick; o/u 55.0
• Implied totals: GB 27.5, TB 27.5
• The line wants us to believe: These teams are even. Really?! The undefeated Packers are on the same level as a Buccaneers team that lost to the Bears last week?! It tells me the oddsmakers really, really want your money on the Packers. Both teams are getting healthy on offense, but if the Buccaneers secondary plays as well as it has for most of the year (five passing touchdowns allowed in their past four), then maybe they are the right side to be on.
• Toughest lineup decision: Ronald Jones — Start. It's going to be fascinating to see what kind of split we see in Tampa's backfield this week, with Leonard Fournette presumably back and Jones coming off consecutive 100-yard games. Has he done enough to earn Bruce Arians' trust, and if so, what does that mean for Fournette? 
• What we're watching for: I've been harping on Mike Evans' usage all season, so that's the key thing I'll be watching for. Evans has played through hamstring and ankle injuries, so that could explain why his target share and average depth of target are both down, but it could also be due to the switch from Jameis Winston to Tom Brady. There's a lot less available production in this passing game with that switch, and if the Bucs continue to spread it around, Evans could be a major disappointment moving forward, so I'd like to see Brady look his way more down the field. 
• Injuries: Davante Adams (hamstring) — Full participant in practice, fully expected to return in Week 6 … Mike Evans (ankle)/Chris Godwin (hamstring) — Both were limited Thursday, but there does appear to be optimism that both will be able to go. Evans is obviously more likely of the two to play … Leonard Fournette (ankle) — Limited both Wednesday and Thursday, but the fact that he was available in an emergency role last week makes me think Fournette will be available … Rob Gronkowski (shoulder) — Limited participant both Wednesday and Thursday, though there's probably no need for you to consider starting him anyway. 

• Line: SF +3.5; o/u 51.5 
• Implied totals: SF 24, LAR 27.5
• The line wants us to believe: The Niners' blowout loss last week was an aberration. Maybe the truth is that they're expected to play their division rivals a lot closer. One thing's for sure -- it's much easier for the public to take the Rams here than the 49ers. That absolutely feels like a sucker bet. I would imagine Raheem Mostert and the San Francisco defense will play better than anyone realizes.
• Toughest lineup decision: Rams running backs — Sit. Again, you might not have a choice, and if you need to trust one, Darrell Henderson is the obvious answer. However, Malcolm Brown hasn't ceded his passing downs role, and Sean McVay has talked about wanting to get Cam Akers more involved now that he's healthy. It seems like he really does want to go with a hot-hand approach here, which is a nightmare for Fantasy.  
• What we're watching for: Both backfields will be worth watching. The Rams for the reasons stated above, and the 49ers because we saw shockingly little of Jerick McKinnon in Week 5. He showed he is still a dynamic player who could handle a big role with Raheem Mostert missing two games, and then played his second-lowest snap share of the season with Mostert back. Was that just because it was a blowout? Or is McKinnon really just a bit player when Mostert is healthy? 
• Injuries: Jimmy Garoppolo (ankle) — Full participant in practice Wednesday. It's not clear what, exactly, led to Garoppolo's struggles in Week 5 if the ankle is fully healthy. That is a concern in itself. 

• Line: BUF +3.5; o/u 57.5
• Implied totals: BUF 27, KC 30.5
• The line wants us to believe: The Chiefs' loss is the anomaly, not the Bills' loss. Truth is both losses were probably out-of-the-ordinary. Hard to see either team losing two straight, but it's easier for the public to ride the Chiefs. That's by design. Buffalo as a home underdog should be expected to rebound and keep things close. It will help the Bills a lot if John Brown is back.
• Toughest lineup decision: Mecole Hardman — Start. Sammy Watkins is likely to miss at least one game, so Hardman's opportunity to break out is here. Hardman is an electric playmaker, and his role has steadily increased as the season has gone on, so if he's the No. 2 WR — and No. 3 option in the passing game, after Travis Kelce and Tyreek Hill — there's huge upside here. I'm not saying Hardman is a must-start player, but if you're in need of a WR3, he could be a week-winner. 
• What we're watching for: Hardman's usage will be one thing, as will the Bills backfield. Zack Moss should be able to return this week, and he'll do so coming off a game in which Devin Singletary ceded passing work to T.J. Yeldon. That's concerning, given that there was talk in training camp that Moss may be the primary short-yardage back. If Singletary isn't getting heavy passing game work and he's ceding goal-line touches, he's going to be a pretty boring Fantasy option, so let's see what his role looks like if Moss plays. Obviously, if Bell is cleared to play, how much he cuts into Edwards-Helaire's role  will be key, too.
• Injuries: Sammy Watkins (hamstring) — Did not practice Thursday. This could be Hardman's big chance … Zack Moss (toe) — Full participant Thursday, will likely make his return, but you probably don't want to rely on him as anything more than maybe a desperation flex play … John Brown (knee) — Full practice, looks like that'll be just a one-week absence. 

• Line: DAL +2; o/u 55.0
• Implied totals: DAL 26.5, ARI 28.5
• The line wants us to believe: Losing Dak Prescott is a big deal. I mean, of course it is, but enough to make the Cowboys a home underdog against a Cardinals team that has floundered offensively against everyone except the Jets lately? A Cardinals team without pass rusher Chandler Jones for the rest of the season? I could very easily see the Cowboys rally around Andy Dalton and come up with a win.  
• Toughest lineup decision: Andy Dalton — Start. There are other quarterbacks I like more than Dalton this week if you need a starter — Ryan Fitzpatrick and Kirk Cousins among them — but Dalton should be a fine starting option in his own right. The Cardinals just lost their best pass rusher, and this wasn't a particularly fearsome defensive unit with Jones, so I expect Dalton to fare well in his first start for the Cowboys. 
• What we're watching for: How will the Cowboys receiving hierarchy change with Dalton under center? I'm expecting a more conservative approach all around, but will the passing game still be centered around Amari Cooper still? And how will CeeDee Lamb and Michael Gallup be prioritized? And what about Dalton Schultz? It's a confusing situation for now. 
• Injuries: Nothing we need to know about.