Colleagues randomly assigned 150 individuals aged 40 to 70 years with elevated untreated HbA1c to a low-carbohydrate intervention (target <40 net g carbohydrates during first three months; <60 net g for months 3 to 6) or usual diet to examine the six-month change in HbA1c. Participants in the low-carbohydrate group also received dietary counseling.
Researchers conducted a secondary analysis of an eight-week TRE study conducted in adults with obesity. After exclusion of men and perimenopausal women, the remaining women were classified as premenopausal or postmenopausal (12 and 11, respectively).