Plus: extended-release metformin from Sun Pharma available in US; glycemic variability risks; more
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Feb. 29, 2020: Issue #1031

TOP STORIES - Diabetes News & Research

Canagliflozin for Those on Triple Drug Therapy with Uncontrolled Diabetes

Glycemic Variability (GV) Increases Risk For Poorer Outcomes

Medication Adherence and its Effect on Diabetes Outcomes
Letter from the Editor
Feb. 29, 2020 

Today I had a webinar with our interns on diabetes medications, insulin and adherence. Most of the program was on how to make the patient feel like they were part of the solution and take ownership. Like most new medical professionals, they felt that patients would do what was right without question, and have no reason to question why we have them do things.

We spent considerable time talking about medication choices and why patient buy-in was so important for success. We looked at why certain people do better on certain regimens, and why finding the right combination of meds is about more than just what will work, but we also have to take into account what patients will have to do once they start.

One of our former interns, Jordan Boyd, PharmD. Candidate of Florida Agricultural & Mechanical University School of Pharmacy, recently found a great article on how medication regimens affect adherence; I am sharing this with you as I did the interns.

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We can make a difference!

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Dave Joffe

Editor-in-chief


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Newsflash

The only FDA-approved liquid formulation of extended-release metformin from Sun Pharma is now available in the United States.

TOP STORIES - Diabetes News and Research

Canagliflozin for Those on Triple Drug Therapy with Uncontrolled Diabetes
SGLT-2 inhibitors have proved to be successful hypoglycemics, so should they be recommended earlier for those not achieving goal A1c reductions? 
READ MORE
Glycemic Variability (GV) Increases Risk For Poorer Outcomes
Maintaining a steady GV through lifestyle, proper treatment regimen, and responsible dietary nutrition can help manage a type 2 diabetic condition. 
READ MORE
Medication Adherence and its Effect on Diabetes Outcomes
Is there a benefit to keeping it “simple” when determining appropriate regimens for patients with diabetes?  
READ MORE

Fact: Late Bedtimes for Children Increase Risk For Obesity and Diabetes


This study aimed to compare sleep in young children at different obesity risks, which were based on parental weight, as well as to explore the longitudinal associations of sleep characteristics with adiposity.  It included 107 children, of which 43 had normal-weight parents (low obesity risk), and 64 had  parents with overweight or obesity (high obesity risk). Sleep was measured yearly from ages 2 to 6 years by using actigraphy. The outcome variables, also measured annually, were BMI z score and waist circumference.  The researchers were able to objectively measure sleep characteristics via the wrist tracker rather than relying on information relayed by parents and children. 

The results showed that there was no difference in sleep patterns among children at different risks. A higher short sleep duration score was associated with a more significant increase in BMI z score across ages. Independently of sleep duration, a higher late sleep score was associated with more substantial increases in BMI z score, and waist circumference. Moreover, compared with children at low risk and without habitual late sleep, children at high risk and with routine late sleep had more significant increases in BMI z score (0.93; 95% CI 0.40 to 1.45) and waist circumference (3.45 cm; 95% CI 1.78 to 5.12). So, from the results, it was concluded that more frequent exposures to late sleep were associated with more significant increases in adiposity measures from ages 2 to 6 years, particularly in children whose  parents had obesity.Journal of Pediatrics Feb 2020

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:

Antonio Bess, Pharm D Candidate, Florida Agricultural & Mechanical University School of Pharmacy

Jordan Boyd, PharmD. Candidate Florida Agricultural & Mechanical University School of Pharmacy

Alessa Grieff, PharmD Candidate, University of South Florida College of Pharmacy

George McConnell, PharmD. Candidate, LECOM School of Pharmacy

Sandra Zaki, PharmD Candidate, Florida A&M University

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Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
810 Bear Tavern Road Suite 102
Ewing, NJ, 08628
USA
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