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Moderna said it planned to request clearance for its coronavirus vaccine in the U.S. and Europe after a new analysis by the company showed the drug was highly effective in preventing Covid-19, with no serious safety problems. But across America, states are beginning to raise concerns about a shortage of supplies with which to roll out any vaccine as the nation grapples with daily coronavirus fatality rates that have exceeded 2,200. Here is the latest on the pandemic. —David E. Rovella 

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Here are today’s top stories

S&P Global grew out of a firm that provided bond ratings and railroad data. IHS Markit  traces its roots to a British barn. Now, the second-biggest acquisition of 2020 will combine the two into a $39 billion data Goliath.

While stocks slumped Monday, the selling did little to damage a November on Wall Street that will go down in the history books. See it in charts.

The golden age of the City of London may be coming to an end, courtesy of Brexit. Fears that the finance powerhouse will fade into the background are growing as more businesses depart for the European Union and Britain enters the last month of transition without a financial-services deal.

The City of London

The U.S. Congress faces a rapidly approaching deadline to pass a new round of funding for the federal government, with dimming odds of hashing out another coronavirus relief package.

Arizona certified President-elect Joe Biden’s victory there on Monday, dealing the latest blow to President Donald Trump’s scattershot campaign to have the election reversed. That leaves Wisconsin—which Biden also won—as the last contested battleground state to formalize its result.  

Biden rolled out the first set of nominations for his economic team on Monday. One of them, Neera Tanden to lead the Office of Management and Budget, is already being attacked by Republicans.

Neera Tanden, president and chief executive officer of the Center for American Progress 

Photographer: Patrick T. Fallon/Bloomberg

Meet the clean supermajors. They have the clout and financial might of the energy behemoths that dig for oil and gas. But instead of mines and wells, these firms are leading the race to electrify the global economy.

What you’ll need to know tomorrow

What you’ll want to read tonight in Businessweek

Today Is a Good Day to Start a Diet. Seriously

In this season of indoor living and holidays, people pack on pounds that they never manage to drop. It’s worse this year because of Covid-19, with working from home and nervous noshing. In America, the rate of adult obesity is more than 40%. Twenty years ago, it was 30%.

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