An inhalable aerogel loaded with DNA that encodes for the SARS-CoV-2 spike protein successfully induces an immune response against COVID-19 in the lungs of mice. The scientists said its aerogel could be used to create an inhalable vaccine that blocks SARS-CoV-2 transmission by preventing the virus from establishing an infection in the lungs.
Results finding that after two years, not only can the implant survive, but also it does not elicit clinically detectable inflammation or signs of immune rejection, even without long-term immunosuppression.
Scientists have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.