| A new investigation provides evidence that neurons in the brain act as master organizers for clearing the brain of metabolic waste and that they do so by synchronizing their actions to create large rhythmic waves in the interstitial fluid (ISF) during sleep. The study, recently published inNature,was conducted by researchers from Washington University in St. Louis and partially funded by the National Center for Complementary and Integrative Health. Neuronal activity in the brain creates metabolic waste products. The accumulation of metabolic waste is a leading cause of many neurological disorders. Although the glymphatic system has been identified as the brains pathway for clearing waste, there is only limited knowledge about how the brain cleans itself. | 
