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Announcements

New Opportunities for Advancing Pain Science December 30, 2021 From the Hippocratic corpus, the author writes, I consider the responsibility of medicine to be to entirely relieve the suffering of the sick and to blunt the extremities of disease (The Art 3.4-7)1. Note that despite the acknowledgement that disease may only be blunted, in promoting health it is our duty to relieve suffering wherever possible. There has been some success in relieving the suffering due to acute pain, i.e., via local and general anesthesia, non-steroidal anti-inflammatories, and opioids, but we have largely failed in effectively removing suffering due to chronic pain conditions. We need new, nonaddictive acute and more effective chronic pain treatments, and we are approaching a unique opportunity for funding new directions for pain research. This message is jointly authored by NINDS Director Walter J. Koroshetz, NCCIH Director Helene M. Langevin, NIA Director Richard Hodes, NIAMS Director Lindsey A. Criswell, NIDCR Director Rena D'Souza, NIDDK Director Griffin P. Rodgers, and NIH HEAL Initiative Director Rebecca Baker.

January 21 Council Meeting To Focus on Pain Research Partap S. Khalsa, D.C., Ph.D. January 10, 2022 On Friday, January 21, 2022, the National Advisory Council for Complementary and Integrative Health (NACCIH) will hold an online-only meeting. If you are a National Center for Complementary and Integrative Health (NCCIH) grantee, potential grant applicant, member of the public, or other stakeholder, we invite you to attend the Open Session.

Resources for Researchers

New Funding Opportunities

HEAL Funding Opportunities

Training

• HEAL Initiative: National K12 Clinical Pain Career Development Program (K12 Clinical Trial Not Allowed)
• HEAL Initiative: Coordinating Center for National Pain Scientists Career Development (R24 Clinical Trial Not Allowed)
• Emergency Awards: HEAL Initiative: Translational Science Career Enhancement Awards for Early and Mid-career Investigators (K18 Clinical Trials Not Allowed)

Pain Basic and Mechanistic Research

• HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
• Notice of Special Interest (NOSI): BRAIN Initiative: Translation of Groundbreaking Technologies from Early-stage Development through Early Clinical Study via Blueprint MedTech

Pain and Opioid Use Disorder Clinical Research

• HEAL Initiative: HEAL Data2Action Research Adoption Support Center (U2C Clinical Trial Optional)
• HEAL Initiative: HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)
• HEAL Initiative: HEAL Data2Action (HD2A) Data Infrastructure Support Center (U24 Clinical Trial Optional)

Opioid Use Disorder Clinical Research

• HEAL Initiative: Pilot & Feasibility Trials to Improve Prevention and Treatment Service Delivery for Polysubstance Use (R34 Clinical Trial Optional)
• HEAL Initiative: Understanding Polysubstance Use and Improving Service Delivery to Address Polysubstance Use (R01 Clinical Trial Optional)
• HEAL Initiative: Research Networks for the Study of Recovery Support Services for Persons Treated with Medications for Opioid Use Disorder (R24 Clinical Trial Optional)
• HEAL Initiative: Harm Reduction Policies, Practices, and Modes of Delivery for Persons with Substance Use Disorders (R01 Clinical Trial Optional)
• HEAL Initiative: Planning Grants for Efficacy or Effectiveness Trials of Recovery Support Services for Individuals Treated with Medications for Opioid Use Disorder (R34 Clinical Trial Optional)
  
  

Highlighted Funding Opportunities

Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs

• Applicant Assistance Program: The next round of AAP applications will open on January 18, 2022. AAP kickoff webinar will be held on January 14, 2022, 2:00 p.m.-3:30 p.m. ET Register for the webinar.
  
  
• iCORPS: Applications for the secondcohort of I-Corps at NIH program are now open. The receipt date is February 2, 2022,5:00 p.m. ET. Office hours are from 2:00 p.m.-3:00 p.m. ET on January 20, 2022 to answer the applicants questions.

Upcoming Events

January 13 Webinar About Research on Patient-Reported Outcomes

January 13, 2022 at 2:00 p.m. ET

The National Institutes of Health (NIH) will hold a webinar on Thursday, January 13 to discuss a current Notice of Special Interest (NOSI) calling for research to improve the interpretation of patient-reported outcomes at the individual patient level for use in clinical practice.

Webinar speakers will highlight the importance and background of the NOSI and discuss examples of responsive topics, methodologic approaches that might be considered in addressing individual-level score interpretation, and information about receipt dates. The session will end with a panel discussion in which colleagues from across NIH will respond to audience questions. The National Center for Complementary and Integrative Health is one of the NIH Institutes, Centers, and Offices participating in this NOSI.

January 13 Webinar on Preparing, Writing, and Submitting an NIH Grant Application

January 13 from 3:00 p.m.-5:00 p.m. ET

The NIH Pain Consortium will hold a webinar on writing and submitting grant applications. This webinar is designed for researchers with limited experience submitting applications to NIH. Its part of a series designed to inform the pain research community of funding opportunities and other resources provided by NIH.Register for the webinarand visit the Pain Consortium website toview past webinars in this series.

Dont miss these FOAs:

• Notice of Special Interest: NCCIH High Priority Pain Research
• Emergency Awards: HEAL Initiative: Translational Science Career Enhancement Awards for Early and Mid-career Investigators (K18 Clinical Trials Not Allowed)
• HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management (R61/R33, Clinical Trial Required). You can learn more about this FOA from thisintroductory videoand thevideo of an informational webinarheld in December.
• HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

You can view more pain-related FOAs and notices on theNCCIH website.

NCCIH Advisory Council 79th Meeting

January 21, 2022, 11:40 a.m.-4:20 p.m. ET; Virtual

In case you missed it...

NIH Collaboratory Celebrates 10 Years of Rethinking Clinical Trials, Changes Program Name to NIH Pragmatic Trials Collaboratory

The NIH Collaboratory is excited to launch into its tenth year with a new name NIH Pragmatic Trials Collaboratorythat will carry the highly successful program into the future with a continued commitment to transforming clinical research. The past decade has been a productive and prolific period for the NIH Pragmatic Trials Collaboratory. Setting the stage for the future, the NIH Pragmatic Trials Collaboratory has redesigned and enhanced the Living Textbook of Pragmatic Clinical Trials. Users will find a new look and streamlined navigation for accessing the programs extensive collection of resources.Read more about this important milestone for the NIH Pragmatic Trials Collaboratory.