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By Dan Donahue, NBC Nightly News

Good Tuesday afternoon. A manhunt is underway for the suspect who shot and injured at least 10 people on a New York subway train, inflation has hit a new 40-year high, and Al Roker is tracking a historic blizzard and severe storm threat.

Here is what’s in our Nightly Rundown.

10 shot on New York City subway, urgent manhunt for suspect

At least 10 people were shot and six others injured when a man wearing a gas mask set off a smoke device and opened fire on a moving New York City subway train during this morning’s rush hour, authorities said.

The shooter remains on the loose at this hour and is the subject of an all-out manhunt, according to the NYPD.

NYPD Commissioner Keechant Sewell said the train was pulling into the 36th Street Station in Brooklyn’s Sunset Park neighborhood when the violence began.

“The suspect was in the train car, the shooting began in the train car,” Sewell said during a news conference.

“As the train was pulling into the station, the subject put on a gas mask. He then opened a canister that was in his bag and then the car began to fill with smoke. After that he began shooting."

Video posted on social media shows the train arriving at the station and passengers fleeing the smoke-filled car. Some can be seen collapsing onto the platform.

A few passengers boarded a second train across the platform to escape, law enforcement sources told NBC New York.

A gun was recovered at the scene, along bag containing other smoke canisters and fireworks, according to law enforcement officials.

The NYPD said there are currently no known explosive devices on subway trains, and this incident is not being investigated as an act of terror at this time. The motive is under investigation.

Video shows aftermath of NYC subway shooting in Brooklyn

Consumer prices continued to skyrocket in March, rising 8.5 percent from a year ago, and the fastest annual gain since December 1981.

Gas prices jumped 48 percent year-over-year, and climbed 18.3 percent from February, according to the new figures from the Bureau of Labor Statistics.

Rents also climbed 5.1 percent in March year-over-year, compared with 4.2 percent in February. The average rent for a two-bedroom home in the U.S. is nearly $2,000, according to Rent.com — up 22 percent year-over-year.

Other categories that saw increases include: groceries, up 10 percent; new cars, up 12.6 percent; and home furnishings, up 10.8 percent.

The U.K. and Australia are examining reports that chemical weapons were used by Russian forces in the besieged southern Ukrainian port city of Mariupol.

The U.S. cannot confirm whether chemical agents were used, but it is still evaluating and monitoring reports, a senior defense official told NBC News.

A Ukrainian unit in Mariupol claimed Russian forces deployed “a poisonous substance of unknown origin,” but offered no evidence.

The reports were denied by a leader of Russian-backed separatist forces in the region.

Ukrainian President Volodymyr Zelenskyy said he takes the reports of chemical weapons being used “as seriously as possible.”

The mayor of Mariupol said today the civilian death toll in Mariupol could be between 20,000 and 22,000.

In Russia today, Vladimir Putin declared that peace talks had reached a “dead end,” and vowed to continue the Ukraine offensive until Russia’s goals are met.

Al Roker is tracking a massive system putting 45 million people at risk for severe storms along a 1,000-mile stretch from southern Minnesota to the Gulf Coast.

The storms are expected to begin hitting this afternoon, with the potential for tornadoes, high winds and very large hail.

On Wednesday, the risk expands to 60 million people from the Great Lakes to the Gulf Coast. Damaging winds exceeding 75 mph will be the greatest risk, followed by strong tornadoes and very large hail.

A major winter storm is also expected to impact portions of the northern Rockies today and the Northern Plains and Upper Midwest through Thursday.

What else we’re watching:

Oklahoma’s Republican governor today signed a near-total ban on abortion, punishable by up to 10 years in prison.
The number of global Covid cases surpassed 500 million today, according to figures from Johns Hopkins University.
U.K. Prime Minister Boris Johnson will be fined by police for breaking his own Covid lockdown rules, after an inquiry into 10 Downing Street’s “partygate” scandal.
New York Lt. Gov. Brian Benjamin was arrested today in an alleged campaign finance scheme, officials said. Benjamin pleaded not guilty and released on $250,000 bail.

Watch us this evening at 6:30 p.m. ET / 5:30 p.m. CT on NBC, or check your local NBC station listing. After the broadcast, access Nightly News video on NBCNightlyNews.com or the NBC News app.

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