Five days after it was approved for use in the UK, the first doses of the Oxford coronavirus vaccine will be given to patients later. It's a "pivotal moment", according to Health Secretary Matt Hancock, as infections continue to surge. More than half a million doses of the vaccine are ready to go, with care home residents and staff, people aged over 80, and NHS workers at the front of the queue. Some 730 vaccination sites have already been established, we're told, with the total set to surpass a thousand later this week.
How fast can the NHS go? Ultimately, it wants to get to two million doses a week and a rapid increase in the vaccination rate is expected in the coming days. Our health correspondent Nick Triggle says the limiting factor may well be supply, given global demand for the jabs.
Why is the Oxford vaccine so important? Well, crucially, it can be kept at normal fridge temperatures, making it easier to distribute and store than the Pfizer jab. It's also cheaper per dose. Find out more about how it was developed, and when you might receive one.

The vaccine news may be positive, but few deny the coronavirus situation in the UK right now is bleak and likely to remain so for the rest of the winter. On Sunday, more than 50,000 new cases were recorded for the sixth day running. It's prompted Labour to call for a third national lockdown in England, with renewed emphasis on the "Stay at home" message. Northern Ireland and Wales already have their own lockdowns in place, and First Minister Nicola Sturgeon is expected to announce further measures for Scotland later.
Many of England's primary schools are reopening, but rows continue about whether they should. Teaching unions say no. Secondaries are staying closed except for vulnerable and key worker children, and in some tier four areas primaries are also not open to most pupils. Head teachers are warning of a "confusing picture" for parents and staff, while the TUC is urging firms to furlough parents whose children have to stay at home. If you're finding yourself homeschooling once again, BBC Bitesize can help.
The prime minister has admitted virus restrictions are likely to get tougher in the coming weeks, so what might that mean? Well, the obvious next step would be to move more areas into tier four - a reminder of what that means - but our science editor David Shukman says there are other steps under discussion too.

US Vice-President elect Kamala Harris has accused Donald Trump of a "bold abuse of power" after he was recorded putting pressure on a senior election official in Georgia to overturn Joe Biden's victory in the state. The Washington Post released audio of the outgoing president calling on Brad Raffensperger to "find" him nearly 12,000 votes. Mr Trump claimed the official was unwilling to answer questions about electoral fraud.
So far, US courts have rejected 60 challenges to Mr Biden's win and our North America reporter Anthony Zurcher says Mr Trump is now resorting to desperate measures. The brazenness of the call may make it more difficult for the president to rally political support to his cause, he adds.
Mr Biden is due to be inaugurated on 20 January. Here's what we expect to happen that day, and what's in store for him once he takes office.

The front pages seem to broadly agree that coronavirus restrictions are likely to be tightened. "Happy New Tier" is the Metro's headline, while the Daily Telegraph warns the "threat of national lockdown looms again", with countrywide school closures possible from as early as this week. The paper also says discussions have begun about the return of shielding. The Times tells readers to "stand by for tough new Covid curbs", and expects a decision from the prime minister by Wednesday. "Class chaos" is how the Daily Mirror sums up the "PM's schools debacle". The Guardian agrees the "schools crisis" is growing, quoting some council leaders who say the argument for reopening classrooms amid surging infection rates "does not stack up". Some papers try to strike an optimistic note, though, hailing the Oxford vaccine. The Sun calls it a "vital shot in the arm in Britain's Covid fight". Elsewhere, the Daily Mail leads with its campaign to help the four million people it says are stuck in "fire-trap homes" after the Grenfell disaster.

For years, India's artisanal pen makers have worked in relative obscurity, operating out of hole-in-the-wall workshops with a handful of employees. Then they began selling on ebay and Amazon, and started making their mark around the world. Elsewhere, see striking night vision images shot by photographer Hugh Kinsella Cunningham when he joined UN peacekeepers in DR Congo. And finally, we continue our Sound of 2021 countdown, revealing which artist came in at number four.

From elsewhere