This week on Q+A we cover the big issues, including health, equality and the worsening humanitarian crisis in the Middle East. As the situation in Gaza deteriorates and Israel steps up its response against Hamas, there are increased calls for humanitarian pauses to the conflict. Will the increasing international pressure have any effect?

Médecins Sans Frontières is among those calling for a ceasefire, as doctors struggle to treat the injured with limited medical equipment or anaesthetic. Aid convoys have kept up a limited delivery of much-needed supplies, but they are far short of the growing demands. What does this mean for a civilian population already at the brink?

Here at home, the government is grappling with the issue of vaping, amid reports that it's reaching epidemic levels among young people. It's a looming health catastrophe, but how effective will regulation be with a thriving black market?

And a long-awaited increase to the bulk-billing incentive has begun, but will it lead to better access to fee-free GP visits for some of the nation's most vulnerable?

Q+A is live from Sydney tonight, Monday November 6, at 9.35pm AEDT.

Joining Patricia Karvelas on the panel live in Sydney:

Mark Butler, Minister for Health & Aged Care
Dai Le, Independent MP for Fowler
Keith Wolahan, Liberal Member for Menzies
Jennifer Tierney, Executive Director, Médecins Sans Frontières Australia
Matilda Boseley, Journalist, Guardian Australia

If you would like to submit a question for consideration, please submit via our website for the chance to ask the panel.

Each week, Q+A selects our top question to highlight in the newsletter. Scroll down to watch Monday's toughest question asked by Francesca Dias, who shared her recent experience of using facial recognition software.

Watch Q+A Monday at 9.35pm AEDT on ABC TV or ABC iview. 

Looking forward to hearing your questions.