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| ‘Frameshifting’ therapy for mast cell cancers reduces size, spread Posted: 10 Aug 2021 01:13 PM PDT A potential new treatment for mast cell cancers reduces the number of mast cells by 'mutating' the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation. The method, known as frameshifting, changes the pre-mRNA so that the mature mRNA is degraded and any protein produced from its instructions is altered and inert. In a mouse model, frameshifting directed at the c-KIT gene reduced mast cell tumor size and prevented infiltration into other organs. |
| Posted: 10 Aug 2021 01:13 PM PDT Novel camera detects the birth of high-energy runaway electrons, which may lead to determining how to prevent damage caused by the highly energetic particles. |
| System trains drones to fly around obstacles at high speeds Posted: 10 Aug 2021 12:34 PM PDT A new algorithm helps drones find the fastest route around obstacles without crashing. The system could enable fast, nimble drones for time-critical operations such as search and rescue. |
| The movement of small water droplets is controlled by means of a magnet Posted: 10 Aug 2021 11:31 AM PDT A new study has presented and characterized the formation and properties of a superparamagnetic ring, which fits snugly around a drop of water due to liquid-liquid interaction, and allows the drops to be physically manipulated. |
| Researchers use artificial intelligence to unlock extreme weather mysteries Posted: 10 Aug 2021 11:31 AM PDT A new machine learning approach helps scientists understand why extreme precipitation days in the Midwest are becoming more frequent. It could also help scientists better predict how these and other extreme weather events will change in the future. |
| Insidious coral killer invading Palmyra Atoll reef Posted: 10 Aug 2021 11:31 AM PDT The reefs at Palmyra Atoll, a small outlying atoll in the equatorial Pacific Ocean, have been undergoing a shift from stony corals to systems dominated by corallimorphs, marine invertebrates that share traits with both anemones and hard corals. Marine biology researchers discovered that although the invading corallimorph is the same species that has been there for decades, its appearance recently changed, and it became much more insidious. |
| Dragonfly mission to Titan announces big science goals Posted: 10 Aug 2021 11:30 AM PDT The NASA Dragonfly mission will send a rotorcraft relocatable lander to the surface of Saturn's moon Titan in the mid-2030s; it will be the first mission to explore the surface of Titan. |
| Atomic nuclei and leptons: Milestone in the calculation of cross sections Posted: 10 Aug 2021 11:30 AM PDT A team has succeeded in computing how atomic nuclei of the Calcium element behave in collisions with electrons. Results agree very well with available experimental data. For the first time, a calculation based on a fundamental theory is capable of correctly describing experiments for a nucleus as heavy as Calcium. Of particular relevance is the potential that such calculations could have in the future to interpret neutrino experiments. |
| Enzyme treatment of skin samples improves microbiome analysis Posted: 10 Aug 2021 10:08 AM PDT Healthy skin has a bacterial shield to protect against germs: the microbiome. This complex assembly of microorganisms was previously believed to be difficult to decipher. A team of researchers has now succeeded in using the enzyme benzonase to identify the living bacteria in skin swabs through sequencing. Their method opens up new possibilities for diagnosis and treatment in dermatology. |
| Metamaterials research challenges fundamental limits in photonics Posted: 10 Aug 2021 10:07 AM PDT Researchers are proposing a new way to modulate both the absorptive and the refractive qualities of metamaterials in real time, and their findings open intriguing new opportunities to control, in time and space, the propagation and scattering of waves for applications in various areas of wave physics and engineering. |
| Researchers discover how to stick sensors to skin without adhesive Posted: 10 Aug 2021 10:07 AM PDT Imagine if you could attach something to your skin without needing glue. A biosensor, a watch, a communications device, a fashion accessory -- the possibilities are endless. Thanks to a discovery, that time could be closer than you think. |
| Urban experimentation can help develop sustainable policies Posted: 10 Aug 2021 09:11 AM PDT A new study offers an outline of the requirements and research challenges involved in designing effective policies to meet sustainability goals for cities. |
| Through the looking glass: Unravelling how ions move in phosphate glass Posted: 10 Aug 2021 09:11 AM PDT Phosphate glasses are expected to have applications in a variety of fields. To improve their functionality, it is necessary to determine the association between their structure and ion diffusion characteristics. Recently, using first-principles molecular dynamic simulations, researchers have provided novel insights into the ion diffusion mechanisms of phosphate glass, suggesting that ionic conductivity and glass solubility can be manipulated by controlling the morphology of the material. |
| 'Why you gotta be so rude?' Study highlights 'vicious cycle' of workplace incivility Posted: 10 Aug 2021 09:10 AM PDT Workplace incivility is on the rise, and a new study found that employees who experience or witness incivilities are more likely to be uncivil to others -- a worrying trend that could intensify as people return to in-person work. |
| Ultraprocessed foods now comprise 2/3 of calories in children and teen diets Posted: 10 Aug 2021 08:09 AM PDT Results from two decades of data show ultraprocessed foods have become a larger part of kids' and teens' diets with disparities by race and ethnicity. |
| Deletion of single gene promotes growth of functional lymphatic valves Posted: 10 Aug 2021 08:09 AM PDT A preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema. Valve loss or dysfunction that disrupts the flow of lymph fluid is strongly associated with lymphedema in patients. But no one has discovered whether new valves can be grown or if defective ones can be fixed. The new study, using a model of human primary lymphedema, shows that both are possible. |
| Only one human fat cell subtype responds to insulin stimulation Posted: 10 Aug 2021 08:09 AM PDT It is well known that fat cells can influence our sensitivity to insulin. Now, researchers have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called AdipoPLIN, that responds to insulin. The findings may be relevant for future treatments of metabolic diseases such as Type 2 diabetes. |
| Researchers develop real-time lyric generation technology to inspire song writing Posted: 10 Aug 2021 07:47 AM PDT Music artists can find inspiration and new creative directions for their song writing with technology. |
| Speed and absorption key to optimizing new type of rechargeable battery Posted: 10 Aug 2021 07:47 AM PDT Rechargeable, lithium sulfur batteries are promising candidates to sustainably meet the world's energy demands, and a new study has put them one step closer to becoming readily available. |
| Beige fat 'indispensable' in protecting the brain from dementia Posted: 10 Aug 2021 07:46 AM PDT Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection from dementia. |
| Pest attack-order changes plant defenses Posted: 10 Aug 2021 07:46 AM PDT The dining time of different insects impacts a plant's defenses and nutritional quality -- a complexity uncovered in new research with implications for pest management strategies. |
| Molecular mechanism that mediates a link between fetal conditions and later health Posted: 10 Aug 2021 07:46 AM PDT Periconceptional conditions are known to influence the later health of individuals. Fetal growth and development set the framework for future health, but recently it has also been suggested that the individual is epigenetically prepared for the conditions in which he or she will be born. If food or nutrient intake is scarce during pregnancy, the emerging individual seems to be better prepared to absorb energy and nutrients than a similar individual whose developmental conditions have been more favorable. |
| Cellular filaments keeping the pace Posted: 10 Aug 2021 07:46 AM PDT A new model describes the coordination of beating cilia allowing to predict their functional behavior. Researchers analyzed the formation of metachronal waves in arrays of cilia and how external cues might influence them. The model allows to better understand the crucial role that cilia play in many biological processes and lays the foundation for its manipulation. This may ultimately improve the corresponding medical diagnostics and treatments, but also helps in the design of artificial systems used in microscale engineering. |
| Natural language processing research: Signed languages Posted: 09 Aug 2021 03:10 PM PDT Advancements in natural language processing (NLP) enable computers to understand what humans say and help people communicate through tools like machine translation, voice-controlled assistants and chatbots. |
| High BMI causes depression – and both physical and social factors play a role Posted: 09 Aug 2021 11:40 AM PDT A largescale new study provides further evidence that being overweight causes depression and lowers wellbeing and indicates both social and physical factors may play a role in the effect. With one in four adults estimated to be obese in the UK, and growing numbers of children affected, obesity is a global health challenge. While the dangers of being obese on physical health is well known, researchers are now discovering that being overweight can also have a significant impact on mental health. |
| Spotting — and hearing — heart attacks before they strike Posted: 09 Aug 2021 08:28 AM PDT If heart attacks blared a warning signal, patients would have a better chance of avoiding them. That's the idea behind a new imaging technique. |
| Posted: 09 Aug 2021 07:04 AM PDT Emergency department physicians who saw patients with a pulmonary embolism -- a blood clot in the lung -- were about 15% likelier over the next 10 days to test subsequent patients for the same thing. |
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