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| Artificial intelligence successfully predicts protein interactions Posted: 16 Nov 2021 02:51 PM PST Researchers used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions. The study identified more than 100 probable protein complexes for the first time and provided structural models for more than 700 previously uncharacterized ones. Insights into the ways pairs or groups of proteins fit together to carry out cellular processes could lead to a wealth of new drug targets. |
| Research in mice shows how diet alters immune system function through a gut microbe Posted: 16 Nov 2021 02:50 PM PST Research in mice demonstrates how diet alters a gut microbe molecule that, in turn, prompts immune cells to downregulate inflammation. The study elucidates molecular mechanism behind long-standing belief that diet, microbiota, and immunity influence one another in myriad ways. If affirmed in larger animals and humans, the findings could inform the design of small-molecule drugs that regulate immune response to treat inflammatory conditions |
| Why drug used to treat critically ill COVID-19 patients may only benefit males Posted: 16 Nov 2021 02:50 PM PST A new study shows how dexamethasone, the main treatment for severe COVID-19 lung infections, alters how immune cells work, which may help male patients, but has little to no benefit for females. |
| Posted: 16 Nov 2021 02:50 PM PST A study of more than 200,000 U.S adults hospitalized with COVID-19 finds that, overall, patients taking immunosuppressive drugs do not face increased risk of being put on a ventilator or death. |
| Finding the missing piece in global oil life-cycle assessment Posted: 16 Nov 2021 02:50 PM PST New research offers a closer look at the relationship between decreasing demand for oil and a resilient, varied oil market -- and the carbon footprint associated with both. |
| New screening process could lead to next-generation therapeutics for a broad spectrum of diseases Posted: 16 Nov 2021 02:50 PM PST Researchers have developed a high-throughput screen methodology to identify compounds affect a key G protein coupled receptor (GPCR) rhodopsin (Rh). GPCRs mediate many important physiological functions and are considered to be one of the most effective therapeutic targets for a broad spectrum of diseases, ranging from diabetes to immune system disorders. |
| Invention lets people pay for purchases with a high-five Posted: 16 Nov 2021 02:50 PM PST Imagine your car starting the moment you get in because it recognizes the jacket you're wearing. Consider the value of a hospital gown that continuously measures and transmits a patient's vital signs. These are just two applications made possible by a new 'body area network'-enabling fabric. |
| Common gene variants linked to sepsis and COVID-19 severity in African Americans Posted: 16 Nov 2021 02:50 PM PST Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, researchers have found. |
| Ever been lost in the grocery store? Researchers are closer to knowing why it happens Posted: 16 Nov 2021 02:47 PM PST A new study suggests that the brain differentiates very similar environments -- such as two stores from the same supermarket chain -- as if they were even more different than two places that are nothing alike. |
| Posted: 16 Nov 2021 12:23 PM PST Using a new model of brain activity, computational neuroscientists are exploring striking bursts of activity in the human brain that have not been examined before. These bursts may have potential to serve as biomarkers for brain disease and conditions such as depression, schizophrenia, dementia, and ADHD. |
| Posted: 16 Nov 2021 12:23 PM PST Researchers have revealed a striking pattern following a functional screen of extracts from plants collected in Muir Woods National Monument, in coastal redwood forest land in California. They found plants with a long history of use by Native Americans as topical analgesics, were often also used as gastrointestinal aids. |
| Seismic shockwave pattern may be redirecting earthquake damage Posted: 16 Nov 2021 11:48 AM PST According to physics, seismic waves from earthquakes should travel in a four-leaf clover pattern, but in the real world they behave more like ripples in a pond. New research has found the pattern hidden among low-frequency seismic waves, the kind that can topple buildings. The study looked at small earthquakes in northern Oklahoma and could change the way scientists think about potential damage from earthquakes. |
| Coffee and tea drinking may be associated with reduced rates of stroke and dementia Posted: 16 Nov 2021 11:48 AM PST Drinking coffee or tea may be associated with a lower risk of stroke and dementia, according to a new study. Drinking coffee was also associated with a lower risk of post-stroke dementia. |
| Game theory and economics show how to steer evolution in a better direction Posted: 16 Nov 2021 11:48 AM PST Human behavior drives the evolution of biological organisms in ways that can profoundly adversely impact human welfare. Understanding people's incentives when they do so is essential to identify policies and other strategies to improve evolutionary outcomes. In a new study, researchers bring the tools of economics and game theory to evolution management. |
| Synthetic biology yields easy-to-use underwater adhesives Posted: 16 Nov 2021 10:17 AM PST Researchers have used synthetic biology to bring together the best of spider silk and mussel foot protein in a biocompatible adhesive. |
| Unique fossil: Seeds sprouting from an amber-encased pine cone Posted: 16 Nov 2021 10:17 AM PST New research has uncovered the first fossil evidence of a rare botanical condition known as precocious germination in which seeds sprout before leaving the fruit. |
| Making solar energy even more sustainable with light-powered technology Posted: 16 Nov 2021 10:17 AM PST Scientists have identified a new process using coordination materials that can accelerate the use of low-cost, Earth-abundant materials with the potential to transform the energy sector by replacing silicone-based solar panels. |
| A better-fitting molecular ‘belt’ for making new drugs Posted: 16 Nov 2021 10:17 AM PST The most common pharmaceuticals on the market are made by chaining together rings of molecules to create the drugs that treat conditions including pain, depression and leukemia. But creating those rings and forming them in a way that is tailored to each individual disease has always been a cumbersome and expensive process in medicinal chemistry. New research proposes a way to simplify that transformation. The discovery will likely make it easier to produce new drug candidates, the researchers say. |
| Researchers develop rapid computer software to track pandemics as they happen Posted: 16 Nov 2021 10:15 AM PST Researchers have created lightning-fast computer software that can help nations track and analyze pandemics, like the one caused by COVID-19, before they spread like wildfire around the globe. |
| Neuroscientists illuminate how brain cells 'navigate' in the light and dark Posted: 16 Nov 2021 08:14 AM PST Researchers have discovered how individual and networks of cells in an area of the brain called the retrosplenial cortex encode this angular head motion in mice to enable navigation both during the day and at night. |
| Climate changed abruptly at tipping points in past Posted: 16 Nov 2021 08:14 AM PST Climate scientists identify abrupt transitions in climate records that may have been caused by the climate system crossing a tipping point. They devised a statistical method to determine whether these transitions are simply noise or evidence of a more significant change. Their method is less error-prone than previous methods, since it doesn't rely on human determination. It also allows comparing different records consistently and can identify important events that may have been overlooked in older studies. |
| Swapping spit helps ants share metabolic labor Posted: 16 Nov 2021 08:13 AM PST Ant colonies use fluids passed mouth-to-mouth to create a colony-wide metabolism, shows a new study. |
| Precise blood pressure control may aid patient recovery from spinal injury Posted: 16 Nov 2021 08:13 AM PST High or low blood pressure in patients during surgery to repair a spinal cord injury may contribute to poorer outcomes, suggests a study published in eLife. |
| Posted: 16 Nov 2021 07:31 AM PST Researchers have modeled that pollutant emissions from the shipping sector increased significantly in major international seaports during the COVID-19 pandemic. |
| Medical training takes a mental toll, but less than a decade ago Posted: 15 Nov 2021 06:29 PM PST A 13-year effort to track the mental health of new doctors in their most stressful time of training shows signs that things have gotten better. But those first-year residents, also called interns, still have a sizable risk of developing depression. And many who do still don't seek help. |
| Scientists identify second HIV patient whose body appears to have rid itself of the virus Posted: 15 Nov 2021 06:29 PM PST In 2020, an untreated HIV patient was identified with no intact copies of HIV genomes in more than 1.5 billion blood cells analyzed, suggesting the virus had been cleared from the patient's body. Researchers now report a second untreated person living with HIV who had no evidence of intact HIV genomes in more than 1.5 billion blood and tissue cells analyzed. |
| Can we tell someone’s cultural group from the way they laugh? Posted: 15 Nov 2021 01:54 PM PST Can we infer someone's cultural group from their laugher, even when we do not know what they are laughing at? And what kind of laughter do we find most positive? A new study shows that our laughter gives us away. The study included Dutch and Japanese producers of laughter and listeners. Listeners could detect whether a laughing person is from their own or another cultural group by only hearing a brief laughter segment. Spontaneous laughter was rated as most positive by both groups. |
| High impact climate events: Better adaptation through earlier prediction Posted: 15 Nov 2021 12:10 PM PST The prediction of high impact climate phenomena can be substantially improved by a new mathematical approach that analyses the connectivity and patterns between geographical locations, scientists say in a new publication. This can potentially save thousands of lives and avoid billions in economic losses. Prediction times for events like El Niño, monsoons, droughts or extreme rainfall could be increased substantially, to a month or in some cases even a year in advance, depending on the type of the event. The new framework can thus become key for improving adaptation to the global warming crisis. |
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