ScienceDaily: Mind & Brain News


Epilepsy research boosts case for new gene therapy for Dravet syndrome

Posted: 19 Jan 2022 06:08 AM PST

New research suggests how a newly developed gene therapy can treat Dravet syndrome, a severe form of epilepsy, and potentially prolong survival for people with the condition.

Astrocyte studies reveal harmful changes in amyotrophic lateral sclerosis

Posted: 18 Jan 2022 05:35 PM PST

Scientists have revealed harmful changes in supporting cells, called astrocytes, in amyotrophic lateral sclerosis (ALS).

Kernel flow: A wearable device for noninvasive optical brain imaging

Posted: 18 Jan 2022 12:48 PM PST

Most noninvasive brain scanning systems use continuous-wave fNIRS, where the tissue is irradiated by a constant stream of photons. However, these systems cannot differentiate between scattered and absorbed photons. A recent advancement to this technique is time-domain (TD)-fNIRS, which uses picosecond pulses of light and fast detectors to estimate photon scattering and absorption in tissues. However, such systems are expensive and complex and have a large form factor, limiting their widespread adoption. To overcome these challenges, researchers have developed a wearable headset based on TD-fNIRS technology.

Students with attention problems more likely to cheat

Posted: 18 Jan 2022 11:59 AM PST

High school students who have trouble paying attention in class are more likely to admit to cheating, a new study shows.

Changes in sleep and biological rhythms from late pregnancy to postpartum linked to depression and anxiety

Posted: 18 Jan 2022 11:59 AM PST

Researchers recruited 100 women, 73 of whom they followed from the start of the third trimester to three months postpartum. They analyzed subjective and objective measures of sleep, biological rhythms, melatonin levels, and light exposure using a variety of tools, including questionnaires, actigraphs (wearable sleep monitors), laboratory assays, and other methods.

Study highlights connections between addictive drugs and brain function in mice

Posted: 18 Jan 2022 11:43 AM PST

Researchers used high-resolution technologies to see how dopamine circuitry in mice is affected by addictive drugs. The results answered older structural questions, while raising new ones about plasticity and recovery in the brain.

Fear of catching COVID-19 heightened Americans' disgust sensitivity

Posted: 18 Jan 2022 09:51 AM PST

A new study suggests that disgust sensitivity -- how intensely a person is repulsed by images, ideas or situations that could be considered really gross or merely unpleasant -- was affected by the pandemic, when concern about catching COVID increased sensitivity to disgust.

Cerebrospinal fluid offers clues to post-COVID 'brain fog'

Posted: 18 Jan 2022 08:14 AM PST

Some patients who develop new cognitive symptoms after a mild bout of COVID have abnormalities in their cerebrospinal fluid similar to those found in people with other infectious diseases. The finding may provide insights into how SARS-CoV-2 impacts the brain.

Boosting T cells improves survival in mice with glioblastoma

Posted: 18 Jan 2022 07:41 AM PST

A new study shows that treatment with an immune-boosting protein called interleukin 7 (IL-7) in combination with radiation improves survival in mice with glioblastoma. The study in mice suggests promise for a phase 1/2 clinical trial that is investigating a long-acting type of IL-7 in patients with glioblastoma.

Harnessing the brain's plasticity to acquire epilepsy resilience

Posted: 18 Jan 2022 07:41 AM PST

Patients with epilepsy must take medicine to manage seizures. Even then, only 65% are able to control their symptoms, rendering invasive surgery the only cure. Now, a research group has investigated a new stimulation paradigm that could cultivate greater resistance to epilepsy.

New MRI technique could improve diagnosis and treatment of multiple sclerosis

Posted: 18 Jan 2022 07:41 AM PST

It is important that multiple sclerosis (MS) is diagnosed and treated as early as possible in order to delay progression of the disease. The technique of magnetic resonance imaging (MRI) plays a key role in this process. A new MRI technique could pave the way to quicker assessment of disease activity in MS.

The circadian clock in heart failure

Posted: 17 Jan 2022 05:58 AM PST

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition. A research team investigated the function of a certain protein on heart disease development in animal models and human patients.

Could concussion be monitored through urine samples?

Posted: 14 Jan 2022 06:28 AM PST

Concussion can be hard to diagnose and track. It doesn't show up on routine brain scans, and there is no definitive diagnostic test. New research could lead to urine 'biomarkers' that could be used to diagnose concussion and monitor recovery. Using proteomics, researchers compared urine samples from college athletes with and without concussion. Two proteins thought to be involved in brain injury repair emerged as reliable concussion predictors.