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An RNA key that unlocks innate immunity Posted: 12 Oct 2018 12:16 PM PDT |
Simple, cost effective treatment following failed back surgery shows promise Posted: 12 Oct 2018 10:53 AM PDT Failed back surgery (continued low back and leg pain after surgery) is relatively common. With each reoperation, success, as defined by pain reduction, becomes less likely and most patients do not improve. However, preliminary studies using a simple procedure to remove scar tissue or adhesions suggests a new treatment could help those with post-surgical, chronic low back pain. |
Sidestepping the pitfalls of overconfidence with plausible deniability Posted: 12 Oct 2018 10:53 AM PDT |
Calm the immune system, halt premature birth Posted: 12 Oct 2018 08:50 AM PDT |
Insights on the effects of exercise on cognitive performance Posted: 12 Oct 2018 08:02 AM PDT |
Does open heart surgery affect cognitive abilities? Posted: 12 Oct 2018 08:02 AM PDT Understanding how heart valve surgery may affect your cognition is important for older adults. To learn more, researchers reviewed studies to see how patients' cognition changed before and after heart valve surgery. They also looked at whether surgeries on two types of heart valves, the mitral or the aortic, were associated with better or worse outcomes. |
Fat: A new player expands our definition of diabetes Posted: 12 Oct 2018 08:02 AM PDT Type 2 diabetes is reaching epidemic proportions around the world. The World Health Organization reports that more than 422 million people suffer from the disease, including over 1.2 million in Australia alone. The consequences of diabetes can be dire (cancer, kidney failure, and heart attacks) and its prevalence is rising fast. There is an urgent need to better understand how diabetes progresses -- and how it might be stopped. |
Oscillations provide insights into the brain's navigation system Posted: 12 Oct 2018 08:02 AM PDT The brain creates a map of our environment, which enables reliable spatial navigation. The Nobel Prize was awarded in 2014 for research into how this navigation system works at the cellular level. Researchers have now shown that the characteristics of this navigation system are also present in brain oscillations that can be measured using depth electrodes in the human brain. The possibility of testing the neuronal navigation system in this way may open up new approaches for the early diagnosis of Alzheimer's disease. |
Cancer stem cells use normal genes in abnormal ways Posted: 12 Oct 2018 08:01 AM PDT |
A new way to create molecules for drug development Posted: 12 Oct 2018 07:22 AM PDT |
Shedding light on gene variants and their connections to health and disease Posted: 12 Oct 2018 07:22 AM PDT NIH's Clinical Genome Resource (ClinGen) and ClinVar programs are addressing a major barrier to incorporating genomic medicine into healthcare, which is a lack of evidence about the relationship between gene variants and diseases. A special issue of Human Mutation highlights the broad array of advances made through these programs, which work in concert to advance knowledge connecting human genomic variation to human health. |
How the grid cell system of the brain maps mental spaces Posted: 12 Oct 2018 07:22 AM PDT How exactly the grid cell system works in the human brain, and in particular with which temporal dynamics, has until now been speculation. A much-discussed possibility is that the signals from these cells create maps of 'cognitive spaces' in which humans mentally organize and store the complexities of their internal and external environments. A team of scientists has now been able to demonstrate, with electrophysiological evidence, the existence of grid-like activity in the human brain. |
'Vampire burial' reveals efforts to prevent child's return from grave Posted: 12 Oct 2018 06:30 AM PDT |
Ketogenic diet appears to prevent cognitive decline in mice, study finds Posted: 12 Oct 2018 06:29 AM PDT |
Clues that suggest people are lying may be deceptive, study shows Posted: 12 Oct 2018 06:29 AM PDT |
Early changes to synapse gene regulation may cause Alzheimer's disease Posted: 12 Oct 2018 06:29 AM PDT New research has revealed a role for splicing proteins in the pathology of Alzheimer's disease. Increased phosphorylation of the SRRM2 protein, seen in AD mouse models and human patients, was found to block its transport to the nucleus. This reduced levels of the PQBP1 protein, causing abnormal changes to the splicing of synapse genes and cognitive decline. These phenotypes were reversed by restoring PQBP1 function, suggesting a possible future treatment for AD. |
Why don't we understand statistics? Fixed mindsets may be to blame Posted: 12 Oct 2018 05:27 AM PDT The first study of why people struggle to solve statistical problems reveals a preference for complicated rather than simpler, more intuitive solutions -- which often leads to failure in solving the problem altogether. The researchers suggest this is due to unfavorable methods of teaching statistics in schools and universities, and highlight the serious consequences when applied to professional settings like court cases. |
Effects of a high-fat diet may be passed on for three generations Posted: 12 Oct 2018 05:27 AM PDT |
Widespread errors in 'proofreading' cause inherited blindness Posted: 12 Oct 2018 05:27 AM PDT |
Caesarean section use has almost doubled globally since 2000 Posted: 11 Oct 2018 04:06 PM PDT Globally, the number of babies born through caesarean section (C-section) almost doubled between 2000 and 2015 -- from 12% to 21% of all births. While the life-saving surgery is still unavailable for many women and children in low-income countries and regions, the procedure is overused in many middle- and high-income settings. |
How parenting affects antisocial behaviors in children Posted: 11 Oct 2018 02:31 PM PDT |
Photoactive bacteria bait may help in fight against MRSA infections Posted: 11 Oct 2018 02:31 PM PDT Researchers are testing whether a light-active version of heme, the molecule responsible for transporting oxygen in blood circulation, may help people infected with MRSA. Photodynamic therapy, or PDT, involves a compound known as a photosensitizer, which can be activated by visible light to kill diseased cells or bacteria. PDT is a clinically proven method for fighting cancer but has not yet been developed for treating MRSA infections. |
Fake or real? New study finds consumers wary of manipulated photos Posted: 11 Oct 2018 02:31 PM PDT |
Cells involved in allergies also play a key role in survival Posted: 11 Oct 2018 11:31 AM PDT |
Human brain cell transplant offers insights into neurological conditions Posted: 11 Oct 2018 11:31 AM PDT |
What pneumococcus says to make you sick Posted: 11 Oct 2018 11:31 AM PDT |
Computational model links family members using genealogical and law-enforcement databases Posted: 11 Oct 2018 11:31 AM PDT |
The metabolome: A way to measure obesity and health beyond BMI Posted: 11 Oct 2018 11:31 AM PDT |
Mouse pups with same-sex parents born in China using stem cells and gene editing Posted: 11 Oct 2018 11:31 AM PDT Researchers were able to produce healthy mice with two mothers that went on to have normal offspring of their own. Mice from two dads were also born but only survived for a couple of days. The work looks at what makes it so challenging for animals of the same sex to produce offspring and suggests that some of these barriers can be overcome using stem cells and targeted gene editing. |
Human retinas grown in a dish explain how color vision develops Posted: 11 Oct 2018 11:31 AM PDT |
New microscope offers 4-D look at embryonic development in living mice Posted: 11 Oct 2018 11:31 AM PDT |
Genetic Achilles heel hurts humans fighting hepatitis C Posted: 11 Oct 2018 11:31 AM PDT |
DNA vaccine against Ebola virus shows potent and long-term efficacy in preclinical studies Posted: 10 Oct 2018 10:24 AM PDT |
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