ScienceDaily: Top Health News

During cell division in a mother cell, the 23 chromosomes that carry the human genome must be first copied and later delivered to two newly forming daughter cells. At least in healthy cells, the result is astonishingly flawless, and no chromosome is ever lost. Not so in malignant cells, where rampant chromosome segregation errors generate a continuous flux of new genetic variants that support metastatic growth and resistance to chemotherapy. A multilayered protein structure called the kinetochore executes the chromosome delivery program.

Scientists have developed a new technique for rejuvenating skin cells. This technique has allowed researchers to rewind the cellular biological clock by around 30 years according to molecular measures, significantly longer than previous reprogramming methods. The partially rejuvenated cells showed signs of behaving more like youthful cells in experiments simulating a skin wound. This research, although in early stages, could eventually have implications for regenerative medicine, especially if it can be replicated in other cell types.

Researchers have developed a wearable device that plays specific sounds to enhance deep sleep. The first clinical study has now shown that the device is effective, but not at the same level of effectiveness for everyone.

A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research.

Mutant mice are providing scientists with a new neurobiological framework to understand the brain changes observed in distractible humans who carry a common gene variant whose frequency has been associated with Attention Deficit Hyperactivity Disorder (ADHD). The scientists demonstrate that mice that express the variant adopt an inattentive phenotype similar to that seen in humans.

Most autoimmune diseases are easy to diagnose but hard to treat. A new article proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune disease.

Researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

Exposure to pollution during pregnancy can have many adverse effects in infants and children that can even extend into adulthood. For example, air pollution exposure is associated with increased risk of low birth weight, preterm birth and risk for developing asthma later in life. Much of this is due to the fast pace of fetal growth and development; however, the exact ways pollutants have these effects and the roles of genes related to immune function and stress response are not fully understood.

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report.

A new artificial intelligence-based approach can predict, significantly more accurately than a doctor, if and when a patient could die of cardiac arrest. The technology, built on raw images of patient's diseased hearts and patient backgrounds, stands to revolutionize clinical decision making and increase survival from sudden and lethal cardiac arrhythmias, one of medicine's deadliest and most puzzling conditions.

Almost one third of babies born with hypoplastic left heart syndrome, or HLHS, die from heart failure before their first birthday. By uncovering cellular processes that drive heart failure in these young patients, a new study may hold the answers to identifying and treating those at highest risk of early death.

Amid parental concerns regarding poor nutrition and lack of cooking skills among youth in Flint, Michigan, a team of local dietitians, chefs, and researchers created Flint Families Cook during the COVID-19 pandemic, a program for families with children ages 8-18 years old, delivered virtually to children and families in their homes.

A recently discovered chemical compound helped elderly mice with obesity lose fat and weight, add muscle and strength, reduce age-related inflammation and increase physical activity, a new study shows.