ScienceDaily: Top News

A scientist comments on the evolving treatment of rectal cancer in light of findings from a study that found the immunotherapy drug dostarlimab was especially effective in a phase II clinical trial of a dozen patients with a subtype of rectal cancer.

A multi-institutional, international study found that testing for ctDNA after surgery and directing chemotherapy to ctDNA-positive patients reduced the use of chemotherapy overall without compromising recurrence-free survival.

A new study has found that RAAS inhibitors, a class of blood pressure-lowering medicine, may be better at reducing the risk of brain aneurysm rupture. People with a brain aneurysm -- a weakened area of a blood vessel -- who were being treated for high blood pressure with medication from the class of drugs called RAAS inhibitors had a significantly lower risk of a ruptured aneurysm compared to those who took other blood pressure medications. These results indicate that RAAS inhibitors may be preferable to other blood pressure-lowering medications and could inform treatment decisions for people with high blood pressure who have unruptured intracranial aneurysms.

A new method to combat malaria which sees the disease turn against itself could offer an effective treatment for the hundreds of millions of people infected globally each year, as the efficacy of current antimalarial drugs weakens. The research has identified an anti-malarial compound, ML901, which inhibits the malaria parasite but does not harm mammalian -- human or other mammals' -- cells.

Bumblebee colonies exposed to glyphosate are significantly affected in times of resource scarcity, according to recent research.

Researchers have created an iron catalyst that can facilitate important chemical reactions in place of the current catalyst, which is made from precious metals.