Cancer Research ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
| | | | We are one month away from our Early Detection of Cancer Conference hosted by the Canary Center at Stanford, OHSU Knight Cancer Institute and us in San Francisco. If you want to be part of this international early detection community register before 4 October.
Closer to home, both the Oxford Centre for Early Detection and Prevention and the Cambridge Early Cancer Institute have upcoming symposia. They will be showcasing the latest early detection research both within their institutions and further afield, with plenty of opportunities for networking.
Finally, congratulations to Professor Serena Nik-Zainal, our Early Detection and Diagnosis Research Committee member who received the 2024 ESMO Award for Translational Research. The prize acknowledges her outstanding work in cancer mutational signature discovery and clinical translation.
I hope to see many of you in San Francisco!
Kind regards,
David Crosby
Head of Prevention and Early Detection Research
Cancer Research UK |
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Upcoming funding deadlines |
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| | Are you curious about AI in cancer early detection? |
| Don’t miss out on the session discussing the promises versus reality of AI for early detection next month.
Our co-chairs Sylvia Plevritis (Stanford University) and Cathie Sudlow (Health Data Research UK) will lead the conversation with Bissan Al-Lazikani (MD Anderson), Su-In Lee (University of Washington) and Jens Rittscher (University of Oxford).
Join our global cancer early detection community in San Francisco between 22 – 24 October to be part of the discussion. |
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| | What can we achieve by collecting data from up to five million people? |
| | “The intended scale and diversity of Our Future Health make it globally unique”, says David Crosby, our Head of Prevention and Early Detection Research, about how this emerging resource can show us the risks and signs of cancer.
This long-term population study will provide data across the UK and allow researchers to look back and see the point at which the signal of cancer emerges, before symptoms and diagnosis. This information could be used in various ways, such as to develop tests that look for hidden cancers.
Our Future Health’s commitment to building a diverse group of participants means that its approach to cancer prevention and early detection can be tailored to specific communities, instead of being one-size-fits-all. |
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| | | | | The Oxford Centre for Cancer Early Detection and Prevention is organising a symposium on the latest research in early cancer detection and prevention.
Hear from the keynote speakers Victor Velculescu (Johns Hopkins University), Sam Janes (University College London), Molly Stevens (University of Oxford) and Georgia Black (Queen Mary University of London).
The event takes place on 10 – 11 December and addresses early cancer biology, cancer detection technologies, cancer vaccines and risk stratification, amongst other topics. | | |
| | | | | | | The Cambridge Early Cancer Institute Annual Symposium is happening next week.
Don’t miss out on this event if you are a researcher, clinician or industry representative with an interest in early cancer research.
There will be an opportunity to hear from a range of speakers, learn about new developments in this field and get an update on the institute's achievements and future plans.
The event features keynote speakers Titus Brinker (German Cancer Research Center) and Professor Simon Leedham (University of Oxford). | | |
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Challenges and lessons in lung cancer screening – a global perspective |
| Are you interested in hearing about advances and challenges in lung cancer screening across the world?
Join a free webinar on 10 October organised by G7 Cancer, a collaboration between seven leading organisations committed to enhancing coordination on cancer research and treatment.
The session will be chaired by Hillary Robbins (International Agency for Research on Cancer) and Professor Rayjean Hung (University of Toronto). |
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| | | | | David Church, Simon Leedham and colleagues at the University of Oxford are developing ‘LynchVax’, the UK’s first vaccine to prevent cancer in people with Lynch syndrome, a heritable genetic condition that increases the risk of bowel and other cancers.
The team has been awarded up to £550,000 by CRUK to carry out the initial underpinning work to test the vaccine’s potential. They will define resulting frameshift peptides in Lynch syndrome associated pre-cancers and determine the mechanisms of immune escape. If successful, the vaccine in development will teach the immune system to identify pre-cancer cells and destroy them before they become cancer.
Meanwhile, the team will also consult the wider Lynch syndrome community to gather their views on a vaccine approach to prevent cancer.
LynchVax is one of several projects funded under our prevention research strategy, which aims to find more precise ways to prevent cancer. | | |
| | | | | | | We’re pleased to announce that the new clinical research funding scheme is now open and has replaced all existing funding schemes with a more flexible and scalable modular-based funding scheme.
The funding scheme is accepting bold and innovative applications to address important clinical questions and further our understanding of cancer biology and treatment. The flexibility of this scheme allows you to ask for what you need to do the research you wish to do.
To apply, complete an expression of interest form and contact the clinical research funding scheme to discuss your proposal and any questions. | | |
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| | | | | After winning the poster prize at our inaugural Cancer Prevention Research Conference in Boston, we caught up with Zhe Huang to talk about his work on investigating the proteomic profiles of prostate cancer, his trip to Boston and the story behind his early career.
Hear more from Zhe about how proteomic research is shaking up the prevention space, as well as advice for those who have newly stepped in the prevention field. | | |
| | | | | | | Congratulations to Federica Lorenzi from the Institute of Cancer Research for winning the image of the month in our Research is Beautiful image campaign.
Federica’s image captured trunk neural crest cells – in a heart shape – obtained from the differentiation of human embryonic stem cells to understand how neuroblastoma forms and develops. The bright heart made of cells reminds Federica of the value of her work in helping the neuroblastoma research community and improving the life of the young patients.
Hint for the upcoming round – images about breast cancer are more than welcome. Drop us an email by 25 September for the chance to become our next winner. | | |
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