By the end of 2023, the world’s wealthiest economies are set to have higher GDP levels than what pre-pandemic projections showed. The same cannot be said for emerging markets and developing economies (EMDEs). From the uneven COVID-19 vaccine rollout to rising income inequality, Indermit Gill, M. Ayhan Kose, and Dana Vorisek discuss the issues facing EMDEs and ways policymakers can address them.