Updates to the ​Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV​ 

The Panel on Antiretroviral Guidelines for Adults and Adolescents (the Panel) updated the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV. For a comprehensive list of recent updates, please see What's New in the Guidelines. The updated Sections are outlined below. 

New Section Added to the Guidelines 

• Transplantation in People With HIV 

Sections With Key Updates 

• What to Start: Initial Combination Antiretroviral Regimens for People With HIV 

• Virologic Failure 

• Optimizing Antiretroviral Therapy in the Setting of Viral Suppression 

• HIV and the Older Person 

• Substance Use Disorders and HIV 

• Transgender People With HIV 

• Hepatitis B Virus/HIV Coinfection 

• Tuberculosis/HIV Coinfection 

• Adherence to the Continuum of Care 

• Drug–Drug Interactions (Tables 24a to 24g) 

Sections With Minor Updates 

• Drug-Resistance Testing 

• Early (Acute and Recent) HIV Infection 

• Women With HIV 

• Cost Considerations and Antiretroviral Therapy 

• Appendix B, Table 12 

Sections Removed From the Guidelines 

• Antiretroviral Components or Regimens Not Recommended as Initial Therapy 

• What Not to Use 

These guidelines are published and updated by the Panel based on the availability of key new clinical evidence on the use of antiretroviral therapy for the treatment of people with HIV. 

To view or download the guidelines, go to the Adult and Adolescent Antiretroviral Guidelines section of the Clinicalinfo website. The guidelines tables and recommendations can also be downloaded as separate PDF files. 

Clinicalinfo welcomes your feedback on the latest revisions to the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV. Please send your comments with the subject line “​Adult and Adolescent Antiretroviral Guidelines​” to HIVinfo@NIH.gov by September 18, 2024.