Update to the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV    - Added isavuconazole sulfate as an alternative treatment for mild-to-moderate pulmonary infections.  Â
- Updated the recommended fluconazole dosing for treatment of coccidioidal meningitis.Â
- Updated information and recommendations on the use of azole antifungals during pregnancy. Â
- Updated alternative regimens for induction, consolidation, and maintenance therapy and recommendations on the timing and frequency of lumbar punctures for central nervous system and/or disseminated disease. Â
- Updated the recommended fluconazole dosing for the treatment of focal pulmonary infiltrates and isolated cryptococcal antigenemia.  Â
- Provided more detailed recommendations for treatment during pregnancy. Â
-  Added alternative maintenance therapy regimens for treatment of severe disseminated disease.  Â
- Updated information on the importance of monitoring serum concentration levels for itraconazole and voriconazoleÂ
These guidelines are published in an electronic format and updated as changes in prevention and treatment science occurs. All updates are developed by the subject matter groups listed in Appendix B. Guideline updates are reviewed by scientific content experts. |
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