Update to the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV   

The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV have been updated.  

Immunizations

• Updated COVID-19 and influenza recommendations with new information on current vaccine formulations and data supporting their use.
• Provided new recommendations for the use of respiratory syncytial virus (RSV) vaccines including data supporting their use. 
• Updated HepBCpG (Heplisav-B) to the preferred hepatitis B vaccine for people with HIV. 
• Added pentavalent meningococcal conjugate vaccine (MenABCWY) recommendations as an alternative to separate administration of quadrivalent meningococcal vaccine and meningococcal group B vaccine.  

These guidelines are published in an electronic format and updated as changes in prevention and treatment science occurs. All updates are developed by the subject matter groups listed in Appendix B. Guideline updates are reviewed by scientific content experts. 

For a list of recent updates, please see What's New in the Guidelines. To view or download the guidelines, go to the Adult and Adolescent Opportunistic Infections Guidelines section of Clinicalinfo’s website. The guidelines tables and recommendations also can be downloaded as separate PDF files.  

Clinicalinfo welcomes your feedback on the latest revisions to the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV. Please send your comments with the subject line “Adult and Adolescent Opportunistic Infection Guidelines” to HIVinfo@NIH.gov by December 3, 2024.