Saturday, March 13, 2021 : Issue #1114

TOP STORIES - Diabetes News & Research

Using NRTIs to Prevent Type 2 Diabetes

Pain Medications in Newly Diagnosed DPN

Vaccine Aims to Lower Type 1 Diabetes Incidence

Letter from the Editor

One of the best things about electronic medical records is the ease of how data can be “sliced and diced” to look for casual cause and effect relationships.

This gives researchers the opportunity to fully examine if a subset of patients can benefit from the use of a medication that has no apparent relationship to a known disease.

This week Destiny Reed, PharmD. Candidate, Florida A&M College of Pharmacy, takes a look at a class of HIV medications and their ability to prevent diabetes, in our Laterpay feature.

*****************************

We can make a difference!

*****************************

Dave Joffe

Editor-in-chief

TOP STORIES - Diabetes News and Research

Using NRTIs to Prevent Type 2 Diabetes
Old drug, new purpose? Analysis found HIV and Hepatitis B patients treated with NRTIs had significantly lower incidence of type 2 diabetes.

Pain Medications in Newly Diagnosed DPN
How often are opioids being initiated for diabetic peripheral neuropathy in newly diagnosed patients?

Vaccine Aims to Lower Type 1 Diabetes Incidence
New vaccines targeting viruses linked with type 1 diabetes may offer protection to patients with high-risk factors.

A recent study published in the Journal of Food Biochemistry found that green tomatoes can induce hypoglycemia (low blood sugar) and antioxidant effects in vitro and in vivo.The green tomato is usually consumed in Mexico, the United States, and Central America. This fruit grows inside a calyx, which is considered an agro‐food waste. Tomatoes are non-starchy and have a low glycemic index, and are a good option for controlling blood sugar in diabetes patients.

Researchers aimed to evaluate the hypoglycemic and antioxidant potential of the green tomato's (P. ixocarpa Brot.) calyxes' extracts. The key findings of the study included:

Extracts decreased the glucose diffusion in a range of 18%–56% compared with the negative control.
Extracts inhibited α‐amylase (above 80%) and α‐glucosidase enzymes (above 90%).
All groups treated with P. ixocarpa calyxes' significantly reduced the glucose levels at 120 min (infusion = 13.3%, M Water = 12.7%, and US Water = 19.4%) in comparison with the negative control, and similar levels to acarbose at 120 min (13.1%).

Currently, no published data supports the green tomato's blood sugar lowering action. The information provided will be useful to nutraceutical applications that allow value‐added products and sustainable green tomato production.

The study titled, "Hypoglycemic and antioxidant effects of green tomato (Physalis ixocarpa Brot.) calyxes' extracts" is published in the Journal of Food Biochemistry. published: February 24, 2021

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:

Alexandria Bartley, PharmD. Candidate, Florida Agricultural & Mechanical University, College of Pharmacy and Pharmaceutical Sciences

Shalonda Kimble, PharmD Candidate, South College School of Pharmacy

Laura Martínez López, PharmD. Candidate 2021, Lake Erie College of Osteopathic Medicine, College of Pharmacy

Destiny Reed, PharmD. Candidate, Florida A&M College of Pharmacy and Pharmaceutical Sciences

Stephen Rubano, PharmD. Candidate, USF Taneja College of Pharmacy

About LaterPay: You will notice that some of our articles are now marked with a small credit card icon. This means you will be asked to pay a small fee to access the full article text (the cost is $0.39 per article, and you will be charged only after you have reached $5.00 in article views). The costs of producing a newsletter like Diabetes in Control have been increasing, which is why we are asking our readers to help support our ability to continue to bring you quality information about diabetes through charging a minimal price to read certain articles. Thank you for helping to support Diabetes in Control.

Your Friends in Diabetes Care
Steve and Dave
Diabetes In Control
www.diabetesincontrol.com

Diabetes In Control
2093 Philadelphia Pike #8370
Claymont, DE, 19703, United States

DiabetesInControl.com | Contact Us
Subscription Center | Update Profile
Unsubscribe

Saturday, March 13, 2021 : Issue #1114

TOP STORIES - Diabetes News & Research

TOP STORIES - Diabetes News and Research

Did You Know? Green Tomatoes May Have Potential to Lower Blood Sugars and Reduce Oxidative Stress:

Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters: