*|FNAME|*, read our latest news: discover how we’re making progress against some of cancer’s toughest challenges

The latest from Cancer Grand Challenges

Clusters of mutations: a new driver of tumour evolution

Challenge: unusual mutation patterns

New research published in Nature pinpoints clusters of mutations as a major driver of tumour evolution. The study also joins the dots between ecDNA and APOBEC3, coining the term ‘kyklonas’ where they occur together. Image credit: Catherine Eng.

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Collaboration and community

A better understanding of how chronic inflammation drives lung cancer

Challenge: cancer causes

The team led by Professor Thea Tlsty at the University of California, San Francisco is investigating how inflammation drives lung cancer by optimising novel models of the human lung.

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Fusobacterium nucleatum: a driver, partner or passenger in colorectal cancer development?

Challenge: microbiota

John Hopkins researchers, Dr Jessica Queen and Dr Cindy Sears discuss how their recent study advances what we knew about a major microbe’s role in colorectal cancer development.

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Spotlight: celebrating women in the community

To celebrate International Day of Women and Girls in Science, we caught up with 5 members of our community to discuss role models, learning from each other and the critical role women play in driving progress in science and technology.

People

Saamin Cheema (centre) is a recent graduate who joined the Cancer Grand Challenges Mutographs team in January 2021 as a data scientist.

Here, she reflects on her first year working with the team to help tackle the "Unusual Mutation Patterns" challenge and her thoughts on the Science Museum Group’s new "Cancer Revolution" exhibition in partnership with Cancer Research UK.

Events

Heading to this year’s AACR Annual Meeting? Make sure to visit us in the exhibition space! We’ll be at stand 1118, joined by members of the IMAXT team taking on our 3D Tumour Mapping Challenge, showcasing their new VR tumour lab technology. Book a slot to be one of the first in the world to step inside a tumour.

Book a slot

Join us on 20 April 2022 to learn more about the association between the microbiome and colorectal cancer.

Hear first-hand from the team of researchers – including Matthew Meyerson and Wendy Garrett - and patient advocates taking on our Microbiota challenge.

This event is delivered in partnership between the Cancer Grand Challenges OPTIMISTICC team and Colorectal Cancer Canada.

Cancer Grand Challenges

2 Redman Place

London, London E20 1JQ

United Kingdom

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