Another week, another round of injuries for Fantasy players to deal with. This time around, it looks like Ben Roethlisberger and Drew Brees could be dealing with significant issues, which would obviously upend two of the most Fantasy-relevant offenses in the league. We dive into the ramifications of both injuries, while also giving you the top early waiver-wire targets plus some winners and losers for Week 2.

Dave Richard takes a look at the impact of Drew Brees' injury before looking ahead to the waiver wire.

Lamar Jackson is proving the doubters wrong, one pass at a time, and the Fantasy ceiling is sky high for this Ravens offense after another dominant showing, Chris Towers says.

Heath Cummings says this Steelers offense won't be the same if Ben Roethlisberger misses extended time.