UC-II® undenatured type II collagen is a patented form of collagen for joint health support. A small amount (40 mg/day) is believed to work by inducing a process known as oral tolerance that ultimately engages the immune system in the repair of its own joint cartilage. This White Paper by Lonza summarizes findings relating to the benefits of oral tolerance. Oral tolerance is an immune process that allows the body to distinguish between innocuous compounds and potentially harmful foreign invaders. Researchers believe UC-II® undenatured type II collagen induces a form of oral tolerance that results from exposure to a compound in small amounts. Animal studies support oral tolerance as the mechanism of action of UC-II® undenatured type II collagen. In vitro studies further support oral tolerance as the means by which UC-II® undenatured type II collagen may exert joint health benefits. Learn more by downloading this white paper.
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